Abstract: The Nelder-Mead simplex method is a well-known algorithm enabling the minimization of functions that are not available in closed-form and that need not be differentiable or convex.

We report the case of long-term persisting rheumatoid arthritis (RA), treated with CD20-CD19 CAR-T when it became associated with diffuse large B cell lymphoma (DLBCL), resulting in a sustained ...

Abstract: Adaptive traffic signal control plays a crucial role in enhancing the traffic situation in urban cities. Recently, reinforcement learning-based methods have demonstrated remarkable ...

Think about placing dots on a flat surface. You want as many pairs as possible to be separated by the same distance. For any amount of dots, what is the greatest possible number of pairs that can be ...

For new discoveries, everyday mysteries, and the science behind the headlines, follow NPR's ShortWave podcast . Over a century ago, the German psychologist Wolfgang Köhler conducted what became a ...