During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.

A team linked to Harvard Medical School has dosed the first patient in a clinical trial designed to reverse cellular aging in ...

Researchers from Sichuan University developed a mineralized DNA hydrogel scaffold that regulates immune responses while sustaining calcium-driven bone regeneration for improved healing of skeletal ...

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary ...

In a breakthrough for longevity science, a reverse-aging treatment has been injected into a human. The technique is a sought-after solution for improving longevity by reprogramming cells. Competitors ...

Aging, at its most fundamental level, is a molecular process. Chemical marks on the genome shift and lose fidelity over time, ...

For those hoping to cure death, and they are legion, a 2016 experiment at the Salk Institute for Biological Studies in San Diego has become liminal — the moment that changed everything. The experiment ...

Researchers have attained the holy grail of cellular reprogramming: inducing pluripotency without using any DNA-based materials. Using only a cocktail of purified proteins and a chemical additive, ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

Proprietary Synthetic Polynucleotide Platform Accelerates Non-Viral, Footprint-Free Induced Pluripotent Stem Cell Generation Amid Surging Commercialization of iPSC Therapies in JapanSEATTLE, June 16, ...