Alberta RNA Research and Training Institute (ARRTI), Department of Chemistry and Biochemistry, University of Lethbridge, 4401 University Drive West, Lethbridge, Alberta T1K 3M4, Canada Article Views ...
ABSTRACT: Zika virus (ZIKV), a mosquito-borne flavivirus, has been associated with benign infections for decades. However, it has become a public health concern due to its association with severe ...
Department of Biochemistry & Biophysics, Texas A&M University, United States; Department of Cell Biology & Genetics, Texas A&M University, United States; ...
Thanks for the help on the last issues, Now I'm trying to get the interaction barcode as an image. I'm running this script now with an sdf file the ligands: import MDAnalysis as mda import prolif as ...
A model of E. coli RfaH bound to Thermus thermophilus TEC was constructed by arbitrarily threading the NT DNA (absent in the X-ray structure) through the TEC (Belogurov et al., 2007). While subsequent ...
Insulin-regulated aminopeptidase (IRAP) is an enzyme with several important biological functions that is known to process a large variety of different peptidic substrates, although the mechanism ...
Identifying which ligands might bind to a protein before crystallization trials could provide a significant saving in time and resources. LigSearch, a web server aimed at predicting ligands that might ...
We describe a graphical system for automatically generating multiple 2D diagrams of ligand-protein interactions from 3D coordinates. The diagrams portray the hydrogen-bond interaction patterns and ...
Equally Potent Inhibition of c-Src and Abl by Compounds that Recognize Inactive Kinase Conformations
Imatinib is an inhibitor of the Abl tyrosine kinase domain that is effective in the treatment of chronic myelogenic leukemia. Although imatinib binds tightly to the Abl kinase domain, its affinity for ...
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