New research shows it’s possible to edit the DNA of human embryos with more precision. But scientists warn it’s still not ...
As genome editing therapies move through clinical trials to regulatory approval, scientists continue the quest for the holy ...
A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of the most common ...
In 2020, Jennifer Doudna won the Nobel Prize in chemistry for her work on the CRISPR-Cas9 gene-editing technology that allows scientists to precisely modify DNA by cutting it at specific locations.
Chemically, DNA isn’t as stable as it looks. One of its four letters quietly breaks down on its own, with no outside trigger. Cells rely on a DNA repair enzyme to catch it before it locks in a ...
A group of scientists led by Dieter Egli has demonstrated base editing in human embryos. Base editing was shown to precisely edit embryonic DNA but also resulted in off-target edits and mosaicism.
Metabolic and genetic abnormalities have long been noted in cardiovascular diseases, but the contribution of mitochondrial genetic (mitochondrial DNA [mtDNA]) variation is understudied. Mitochondrial ...
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