Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

Werner Heisenberg's famous uncertainty principle describes one of the most intriguing features of quantum physics: certain pairs of physical quantities describing a particle, such as position and ...

A laser (purple) is powerfully amplified by highly polished mirrors and focused on the electron beam (blue) to shift its phase and increase the cryo-EM microscope’s contrast, allowing biologists to ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

Although both a SEM and a TEM are electron microscopes, their working principles and images are very different. Whereas an SEM uses secondary electrons ejected after bombarding a sample’s surface with ...