Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

Electron microscope (EM) has revolutionized our ability to visualize the intricate details inside cells. The advancement to 3D electron microscopy, known as volume EM (vEM), has further expanded this ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Princeton scientists are peering into the smallest corners of matter using an exceptional collection of sophisticated microscopes — some so big they fill a room. These remarkable instruments have ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

In 1931, physicists Knoll and Ruska unveiled the first electron microscope, revolutionizing science by using magnetic lenses to overcome the limits of visible light. This groundbreaking invention ...